Inter- and intra-individual variation in urinary excretion of daidzein and equol in female Japanese. (August 2014)

• Record Type: Journal Article
• Authors: Suzuki, Yayoi; Hisada, Aya; Yoshinaga, Jun
• Is Part Of: Biomarkers. Volume 19:Number 5(2014)
• Page Start: 407
• Page End: 410
• Publication Date: 2014-08
• Subjects: Biochemical markers -- Periodicals; 610.28
• DOI: 10.3109/1354750X.2014.922619
• Languages: English
• ISSNs: 1354-750X

Abstract

<abstract> <title>Abstract</title> <p> <italic>Objective</italic>: To evaluate the representativeness of single measurement of urinary soy-isoflavone concentrations for the assessment of long-term intake levels.</p> <p> <italic>Methods</italic>: Five urine samples taken from 14 Japanese female subjects over 2–3 months were measured for daidzein and equol by gas chromatography-mass spectrometry (GC-MS).</p> <p> <italic>Results</italic>: Geometric mean daidzein and equol concentrations of 14 subjects were 582 and 2.66 μg/g creatinine, respectively. Intra-class correlation coefficients for daidzein and equol were 0.355 (95% CI: 0.130–0.649) and 0.741 (0.551–0.891), respectively.</p> <p> <italic>Conclusion</italic>: Single measurement of urinary equol is effective for the assessment of long-term equol status of Japanese subject while that of daidzein is not.</p> </abstract>