Determinants of systolic blood pressure response during exercise in overweight subjects. (August 2014)

• Record Type: Journal Article
• Authors: Bratberg, Jon A.; Bulut, Efraim; Rieck, Åshild E.; Lønnebakken, Mai Tone; Hetland, Trude; Gerdts, Eva
• Is Part Of: Blood pressure. Volume 23:Number 4(2014)
• Page Start: 200
• Page End: 205
• Publication Date: 2014-08
• Subjects: Blood pressure -- Periodicals; Hypertension -- Periodicals; Hypertension -- Periodicals; Blood Pressure -- Periodicals; 612.14
• DOI: 10.3109/08037051.2013.858477
• Languages: English
• ISSNs: 0803-7051

Abstract

<abstract> <title>Abstract</title> <p> <italic>Aim.</italic> Higher systolic exercise blood pressure (BP) is associated with increased cardiovascular risk in hypertension. We aimed at identifying covariates of systolic exercise BP in overweight subjects. <italic>Methods</italic>. 77 subjects with body mass index (BMI) > 27 kg/m<sup>2</sup> and without known heart disease were tested. BP was measured by sphygmomanometry before and at all exercise stages during maximal exercise capacity testing on a treadmill. High peak systolic exercise BP was defined as ≥ 200 mmHg. <italic>Results.</italic> The study population was 48 ± 10 years and included 60% women and 42% with known hypertension. Average BMI was 32.6 ± 4.8 kg/m<sup>2</sup> and clinic BP 132/82 ± 17/8 mmHg. High systolic exercise BP was found in 32%. Subjects with high systolic exercise BP had higher systolic clinic and 24-h ambulatory BP (ABP), as well as lower peak oxygen uptake, compared with subjects with normal systolic exercise BP (all <italic>p < </italic>0.05). In multiple regression analysis known hypertension (β = 0.33), higher systolic ABP (β = 0.22) and high-density lipoprotein (HDL)-cholesterol level (β = 0.23, all <italic>p < </italic>0.05) predicted higher systolic exercise BP independent of sex and peak oxygen uptake (multiple <italic>R</italic><sup>2</sup> = 0.32, <italic>p < </italic>0.001). <italic>Conclusion.</italic> Among overweight subjects, known hypertension, higher systolic ABP and HDL-cholesterol level were the most important factors predicting higher systolic exercise BP.</p> </abstract>