Lung Nodule and Functional Changes in Smokers After Smoking Cessation Short-Term Treatment. (14th September 2014)

• Record Type: Journal Article
• Authors: Maci, Eliana; Comito, Francesca; Frezza, Anna Maria; Tonini, Giuseppe; Pezzuto, Aldo
• Is Part Of: Cancer investigation. Volume 32:Number 8(2014)
• Page Start: 388
• Page End: 393
• Publication Date: 2014-09-14
• Subjects: Cancer -- Periodicals; Oncology -- Periodicals; Medical Oncology -- Periodicals; Neoplasms -- Periodicals; 616.994
• DOI: 10.3109/07357907.2014.919308
• Languages: English
• ISSNs: 0735-7907

Abstract

<abstract> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold> <italic>Background</italic>: Tobacco smoke causes lung disfunction and inflammation. <italic>Methods</italic>: Twenty-two consecutive smokers with undetermined lung nodules were included. All underwent a baseline imaging, exhaled carbon monoxide level evaluation and spirometry, repeated at three months from smoking cessation therapy. <italic>Results</italic>: A significant reduction in size of the lung nodules was reported (<italic>p</italic> = .037) as a trend in number reduction (<italic>p</italic> = .11). A significant increase in blood arterial oxygen pressure (<italic>p</italic> &lt; .0001), heart rate reduction (<italic>p</italic> &lt; .01), and FEV1 increase (<italic>p</italic> &lt; .0001) was recorded. <italic>Conclusions</italic>: Smoking cessation reduces number and size of lung nodules and improves in lung functionality.</bold> </p> </abstract>