Recurrent life‐threatening reactions to platelet transfusion in an aplastic anaemia patient with a paroxysmal nocturnal haemoglobinuria clone. Issue 9 (September 2014)

• Record Type: Journal Article
• Authors: Mohamed, M.; Bates, G.; Richardson, D.; Burrows, L.
• Is Part Of: Internal medicine journal. Volume 44:Issue 9(2014)
• Page Start: 925
• Page End: 927
• Publication Date: 2014-09
• Subjects: Medicine -- Periodicals; 616
• DOI: 10.1111/imj.12528
• Languages: English
• ISSNs: 1444-0903

Abstract

<abstract abstract-type="main"> <title>Abstract</title> <p>A 60‐year‐old woman was diagnosed with non‐severe aplastic anaemia when she presented with anaemia and thrombocytopenia. She developed recurrent life‐threatening hypotensive reactions during transfusion of leukodepleted platelet concentrates, and washed platelet concentrates prevented the development of such reactions subsequently. A paroxysmal nocturnal haemoglobinuria clone was detected on investigating for aplastic anaemia, which has been speculated to play a role in the recurrent hypotensive reactions.</p> </abstract>