Comparison of cure rates and durations of treatment with diphenylcyclopropenone immunotherapy for warts in children/adolescents and adults. (2nd April 2014)

• Record Type: Journal Article
• Authors: Kang, Ho Song; Lee, Min Won; Paek, Jun Oh; Yu, Hee Joon; Kim, Joung Soo
• Is Part Of: International journal of dermatology. Volume 53:Number 10(2014:Oct.)
• Page Start: 1293
• Page End: 1298
• Publication Date: 2014-04-02
• Subjects: Dermatology -- Periodicals; 616.5
• DOI: 10.1111/ijd.12377
• Languages: English
• ISSNs: 0011-9059

Abstract

<abstract abstract-type="main" id="ijd12377-abs-0001"> <title>Abstract</title> <sec id="ijd12377-sec-0001" sec-type="section"> <title>Background</title> <p>Immunotherapy has been used for many years in the treatment of warts. Diphenylcyclopropenone is frequently used as an immunotherapeutic agent.</p> </sec> <sec id="ijd12377-sec-0002" sec-type="section"> <title>Methods</title> <p>A total of 143 patients with 180 cases of warts were included in this study. We divided the patients into two groups: 72 children/adolescents and 71 adults aged 20 and over. We evaluated two types of sensitization reaction, using an erythema and blister index and a pruritus index.</p> </sec> <sec id="ijd12377-sec-0003" sec-type="section"> <title>Results</title> <p>Of the 180 cases of warts, 159 (88.3%) were completely cured: 86 (92.5%) of the 93 cases in children/adolescents and 73 (83.9%) of the 87 cases in adults. The time required for complete cure was 17.72 ± 2.69 weeks in children/adolescents and 22.92 ± 2.59 weeks in adults (<italic>P</italic> &lt; 0.05).</p> </sec> <sec id="ijd12377-sec-0004" sec-type="section"> <title>Conclusions</title> <p>Diphenylcyclopropenone immunotherapy can be used effectively for both children/adolescents and adults. The time required for complete cure is shorter in children/adolescents than in adults.</p> </sec> </abstract>