First in vivo visualization of MRI‐visible IPOM in a rabbit model. Issue 6 (28th January 2014)

• Record Type: Journal Article
• Authors: Otto, Jens; Kuehnert, Nicolas; Kraemer, Nils A.; Ciritsis, Alexander; Hansen, Nienke Lynn; Kuhl, Christiane; Busch, Daniel; Peter Neumann, Ulf; Klinge, Uwe; Conze, Klaus‐Joachim
• Is Part Of: Journal of biomedical materials research. Volume 102:Issue 6(2014:Aug.)
• Page Start: 1165
• Page End: 1169
• Publication Date: 2014-01-28
• Subjects: Biomedical materials -- Periodicals; 610.28
• DOI: 10.1002/jbm.b.33098
• Languages: English
• ISSNs: 1552-4973

Abstract

<abstract abstract-type="main"> <title>Abstract</title> <p>Background: Application of a mesh in presence of pneumoperitoneum may cause deformation or wave formation when gas is released. Moreover, mesh shrinkage during subsequent wound healing cannot be detected <italic>in vivo</italic> without invasive diagnostics. Using MRI‐visible polyvinylidene fluoride (PVDF) mesh, the extend of mesh deformation and shrinkage could be objectified by MRI for the first time. Materials and Methods: Laparoscopic intraperitoneal onlay mesh (IPOM) implantation was performed in 10 female rabbits using ferro‐oxide loaded PVDF meshes. MRI measurements were performed postoperatively at days 1 and 90. After three‐dimensional reconstruction of all MRI images the total surface and the effective surface of the implanted mesh were explored and calculated computer‐assisted. Results: In all cases, the mesh could be identified in MRI. The subsequent three‐dimensional reconstruction always allowed a calculation of the mesh area. In relation to the original size of the used textile implant, we found neither a significant reduction of the effective mesh surface after release of the pneumoperitoneum at day 1 after laparoscopic surgery nor a significant change of the total surface of this large pore mesh by the end of the observation period. Conclusions: <italic>In vivo</italic> investigation of mesh surface via MRI could exclude a significant initial reduction of the effective mesh surface after release of pneumoperitoneum, in this IPOM rabbit model. A further subsequent shrinkage of these large pore PVDF meshes could be excluded, as well. Imaging of MRI‐visible IPOM mesh turned out to be a sufficient tool to objectify mesh configuration and position <italic>in vivo</italic>. © 2014 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 102B: 1165–1169, 2014.</p> </abstract>