Phosphathiahelicenes: Synthesis and Uses in Enantioselective Gold Catalysis. Issue 39 (11th August 2014)

• Record Type: Journal Article
• Authors: Aillard, Paul; Voituriez, Arnaud; Dova, Davide; Cauteruccio, Silvia; Licandro, Emanuela; Marinetti, Angela
• Is Part Of: Chemistry. Volume 20:Issue 39(2014)
• Page Start: 12373
• Page End: 12376
• Publication Date: 2014-08-11
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.201402822
• Languages: English
• ISSNs: 0947-6539

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>Enantiomerically pure thiahelicenes displaying a terminal phosphole unit and a stereogenic phosphorus center have been prepared by oxidative photocyclization of a diaryl‐olefin precursor. Starting from one of these phosphathiahelicene oxides, the corresponding trivalent phosphine–Au^I complex is obtained with complete diastereoselectivity. It affords a new, excellent precatalyst for the enantioselective cycloisomerization of N‐tethered enynes (up to 96 % <italic>ee</italic>).</p> </abstract>