Jugular Valve Incompetence in Transient Global Amnesia. A Problem Revisited. Issue 5 (3rd September 2013)

• Record Type: Journal Article
• Authors: Lochner, Piergiorgio; Nedelmann, Max; Kaps, Manfred; Stolz, Erwin
• Is Part Of: Journal of neuroimaging. Volume 24:Issue 5(2014)
• Page Start: 479
• Page End: 483
• Publication Date: 2013-09-03
• Subjects: Diagnostic imaging -- Periodicals; Nervous system -- Diseases -- Diagnosis -- Periodicals; Imagerie pour le diagnostic -- Périodiques; Système nerveux -- Maladies -- Diagnostic -- Périodiques; Imagerie médicale; Neuroimagerie; Neurologie; Système nerveux; Périodique électronique (Descripteur de forme); Ressource Internet (Descripteur de forme); 616.804754
• DOI: 10.1111/jon.12042
• Languages: English
• ISSNs: 1051-2284

Abstract

<abstract abstract-type="main"> <title>ABSTRACT</title> <sec id="jon12042-sec-0010" sec-type="section"> <title>BACKGROUND AND PURPOSE</title> <p>Previous studies have suggested that transient global amnesia (TGA) may be provoked by cerebral venous congestion due to a reflux during Valsalva maneuver (VM) caused by internal jugular venous valve incompetence (IJVVI). We investigated the hemodynamic consequences of postural changes on IJVVI and on intracranial veins in patients with TGA and control subjects.</p> </sec> <sec id="jon12042-sec-0020" sec-type="section"> <title>MATERIALS AND METHODS</title> <p>IJVVI was assessed by means of extracranial color‐coded duplex sonography during VM in 28 patients with TGA and 25 controls. The basal vein Rosenthal was examined by transcranial color‐coded sonography registering flow velocities (FV) at rest and during VM. These measurements were performed in the supine and in a sitting position.</p> </sec> <sec id="jon12042-sec-0030" sec-type="section"> <title>RESULTS</title> <p>IJVVI was identified in supine position in 19/28 (68%) of TGA patients and in 7/25 (28%) of controls (<italic>P</italic> < .05). Body position had no effect on the detection of IJVVI. Intracranial venous FV at rest and during VM did neither differ between patients and controls, nor between persons with and without IJVVI.</p> </sec> <sec id="jon12042-sec-0040" sec-type="section"> <title>CONCLUSIONS</title> <p>Consistent with results of other groups, we found a significantly higher rate of IJVVI in TGA patients compared to controls. However, we found no differences of intracranial venous circulation between groups nor an effect of body position. This sheds doubt on the assumption of a causative effect of IJVVI in TGA.</p> </sec> </abstract>