Efficacy and tolerability of luliconazole cream 1% for dermatophytoses: A Meta‐analysis. Issue 9 (25th August 2014)

• Record Type: Journal Article
• Authors: Feng, Xiaowei; Xie, Jinwei; Zhuang, Kaiwen; Ran, Yuping
• Is Part Of: Journal of dermatology. Volume 41:Issue 9(2014)
• Page Start: 779
• Page End: 782
• Publication Date: 2014-08-25
• Subjects: Dermatology -- Periodicals; Dermatology -- Japan -- Periodicals; Skin -- Diseases -- Periodicals; 616.5005
• DOI: 10.1111/1346-8138.12577
• Languages: English
• ISSNs: 0385-2407

Abstract

<abstract abstract-type="main" id="jde12577-abs-0001"> <title>Abstract</title> <p>We evaluated the efficacy and safety of luliconazole cream 1% in the treatment of dermatophytoses. According to our meta‐analysis, short‐term treatment of luliconazole cream 1% can result in the complete clearance of dermatophytoses. It showed that 1% luliconazole was more effective than controlled drugs or vehicle (week 4: odds ratio = 1.46, 95% confidence interval = 1.12–1.91), and no more adverse events occurred in the 1% luliconazole group (week 4: odds ratio = 1.01, 95% confidence interval = 0.71–1.44). This effect strengthens the evidence for luliconazole cream 1% being more effective than vehicle, 1% terbinafine, 1% bifonazole, and 0.1% or 0.5% luliconazole.</p> </abstract>