N‐Acyl amino acids and their impact on biological processes. (21st April 2014)

• Record Type: Journal Article
• Authors: Hanuš, Lumír; Shohami, Esther; Bab, Itai; Mechoulam, Raphael; Maccarrone, Mauro
• Is Part Of: BioFactors. Volume 40:Number 4(2014:Jul./Aug.)
• Page Start: 381
• Page End: 388
• Publication Date: 2014-04-21
• Subjects: Vitamins -- Physiological effect -- Periodicals; Trace elements -- Physiological effect -- Periodicals; Growth factors -- Physiological effect -- Periodicals; Plant growth promoting substances -- Physiological effect -- Periodicals; Biochemistry -- Periodicals; Nutritional Physiological Phenomena -- Periodicals; Trace Elements -- metabolism -- Periodicals; Vitamins -- metabolism -- Periodicals; Molecular Biology -- Periodicals; 612.399
• DOI: 10.1002/biof.1166
• Languages: English
• ISSNs: 0951-6433

Abstract

<abstract abstract-type="main"> <title>Abstract</title> <p>Over the last two decades a large number of <italic>N</italic>‐long‐chain acyl amino acids have been identified in the mammalian body. The pharmacological activities of only a few of them have been investigated and some have been found to be of considerable interest. Thus arachidonoyl serine is vasodilatory and neuroprotective, arachidonoyl glycine is antinociceptive, and oleoyl serine rescues bone loss. However, the pathophysiological/biochemical roles of these amides are mostly unknown. © 2014 BioFactors, 40(4):381–388, 2014</p> </abstract>