IgE actions on CD4+ T cells, mast cells, and macrophages participate in the pathogenesis of experimental abdominal aortic aneurysms. Issue 7 (24th June 2014) - Wang, Jing
Abstract This study demonstrates the pathologic role of IgE and its high affinity receptor FcεR1 in AAAs by activating MCs, macrophages but also CD4 and CD8 T cells and suggests anti‐IgE antibodies as future putative therapeutics for treatment.