Cannabidiol can improve complex sleep‐related behaviours associated with rapid eye movement sleep behaviour disorder in Parkinson's disease patients: a case series. (21st May 2014)

• Record Type: Journal Article
• Authors: Chagas, M. H. N.; Eckeli, A. L.; Zuardi, A. W.; Pena‐Pereira, M. A.; Sobreira‐Neto, M. A.; Sobreira, E. T.; Camilo, M. R.; Bergamaschi, M. M.; Schenck, C. H.; Hallak, J. E. C.; Tumas, V.; Crippa, J. A. S.
• Is Part Of: Journal of clinical pharmacy and therapeutics. Volume 39:Number 5(2014:Oct.)
• Page Start: 564
• Page End: 566
• Publication Date: 2014-05-21
• Subjects: Clinical pharmacology -- Periodicals; Chemotherapy -- Periodicals; 615
• DOI: 10.1111/jcpt.12179
• Languages: English
• ISSNs: 0269-4727

Abstract

<abstract abstract-type="main" id="jcpt12179-abs-0001"> <title>Summary</title> <sec id="jcpt12179-sec-0001" sec-type="section"> <title>What is known and objective</title> <p>Cannabidiol (CBD) is the main non‐psychotropic component of the <italic>Cannabis sativa</italic> plant. REM sleep behaviour disorder (RBD) is a parasomnia characterized by the loss of muscle atonia during REM sleep associated with nightmares and active behaviour during dreaming. We have described the effects of CBD in RBD symptoms in patients with Parkinson's disease.</p> </sec> <sec id="jcpt12179-sec-0002" sec-type="section"> <title>Cases summary</title> <p>Four patients treated with CBD had prompt and substantial reduction in the frequency of RBD‐related events without side effects.</p> </sec> <sec id="jcpt12179-sec-0003" sec-type="section"> <title>What is new and conclusion</title> <p>This case series indicates that CBD is able to control the symptoms of RBD.</p> </sec> </abstract>