Inside Back Cover: Development of a 18F‐Labeled Tetrazine with Favorable Pharmacokinetics for Bioorthogonal PET Imaging (Angew. Chem. Int. Ed. 36/2014). Issue 36 (7th July 2014)

• Record Type: Journal Article
• Authors: Denk, Christoph; Svatunek, Dennis; Filip, Thomas; Wanek, Thomas; Lumpi, Daniel; Fröhlich, Johannes; Kuntner, Claudia; Mikula, Hannes
• Is Part Of: Angewandte Chemie international edition. Volume 53:Issue 36(2014)
• Page Start: 9675
• Page End: 9675
• Publication Date: 2014-07-07
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201406154
• Languages: English
• ISSNs: 1433-7851

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p>Bioorthogonal PET probes serve as highly valuable tools in the field of pretargeted molecular imaging. In their Communication on <ext-link ext-link-type="doi" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink">page 9655 ff., </ext-link> H. Mikula, C. Kuntner, and co‐workers describe the development, synthesis, and characterization of a low‐molecular‐weight ¹⁸F‐labeled tetrazine derivative that can be used for bioorthogonal PET imaging of dienophile‐tagged (bio)molecules through the application of in vivo chemistry.<boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgh12z66xfq" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>