A Chromogenic Probe for the Selective Recognition of Sarin and Soman Mimic DFP1. Issue 4 (1st August 2014)

• Record Type: Journal Article
• Authors: El Sayed, Sameh; Pascual, Lluís; Agostini, Alessandro; Martínez-Máñez, Ramón; Sancenón, Félix; Costero, Ana M.; Parra, Margarita; Gil, Salvador
• Is Part Of: ChemistryOpen. Volume 3:Issue 4(2014:Aug.)
• Page Start: 142
• Page End: 145
• Publication Date: 2014-08-01
• Subjects: Chemistry -- Periodicals; 540; 540.5
• DOI: 10.1002/open.201402014
• Languages: English
• ISSNs: 2191-1363

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>The synthesis, characterization and sensing features of a novel probe <bold>1</bold> for the selective chromogenic recognition of diisopropylfluorophosphate (DFP), a sarin and soman mimic, in 99:1 (<italic>v</italic>/<italic>v</italic>) water/acetonitrile and in the gas phase is reported. Colour modulation is based on the combined reaction of phosphorylation of <bold>1</bold> and fluoride‐induced hydrolysis of a silyl ether moiety. As fluoride is a specific reaction product of the reaction between DFP and the −OH group, the probe shows a selective colour modulation in the presence of this chemical. Other nerve agent simulants, certain anions, oxidant species and other organophosphorous compounds were unable to induce colour changes in <bold>1</bold>. This is one of the very few examples of a selective detection, in solution and in the gas phase, of a sarin and soman simulant versus other reactive derivatives such as the tabun mimic diethylcyanophosphate (DCNP).</p> </abstract>