An Efficient Synthesis of Pyrroline‐Fused Acridine Derivatives Catalyzed by Silica Sulfuric Acid. (25th April 2014)

• Record Type: Journal Article
• Authors: Hu, Ming‐Hua; Lin, Wei; Cao, Cheng‐Pao; Huang, Zhi‐Bin; Shi, Da‐Qing
• Is Part Of: Journal of heterocyclic chemistry. Volume 51:Number 1(2014:Jan.)
• Page Start: E227
• Page End: E233
• Publication Date: 2014-04-25
• Subjects: Heterocyclic compounds -- Periodicals; 547.59
• DOI: 10.1002/jhet.2023
• Languages: English
• ISSNs: 0022-152X

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <p>A simple and efficient synthesis of pyrrolo[2, 3, 4‐<italic>kl</italic>]acridine‐1‐one derivatives via the cascade reaction of isatins with enaminones catalyzed by silica sulfuric acid (SSA) has been established. In this reactions, SSA shows a highly catalytic nature: easy to handle procedure, short reaction time, recycle exploitation, insensitivity to air and moisture, and excellent isolated yields. The catalyst could be recycled at least five times.</p> </abstract>