Plasma vitamin D and serum total immunoglobulin E levels in patients with seasonal allergic conjunctivitis. (26th March 2014)

• Record Type: Journal Article
• Authors: Dadaci, Zeynep; Borazan, Mehmet; Kiyici, Aysel; Oncel Acir, Nursen
• Is Part Of: Acta ophthalmologica. Volume 92:Number 6(2014)
• Page Start: e443
• Page End: e446
• Publication Date: 2014-03-26
• Subjects: Ophthalmology -- Periodicals; 617.7005
• DOI: 10.1111/aos.12398
• Languages: English
• ISSNs: 1755-375X

Abstract

<abstract abstract-type="main" id="aos12398-abs-0001"> <title>Abstract</title> <sec id="aos12398-sec-0001" sec-type="section"> <title>Purpose</title> <p>To evaluate plasma 25‐hydroxyvitamin D and serum total immunoglobulin E (IgE) levels in patients with seasonal allergic conjunctivitis (SAC).</p> </sec> <sec id="aos12398-sec-0002" sec-type="section"> <title>Methods</title> <p>This observational case–control study involved 49 patients with SAC without any other ocular and systemic diseases, and 44 consecutive, age‐ and sex‐matched healthy subjects. Plasma 25‐hydroxyvitamin D and serum total IgE levels of all subjects were quantified with electrochemiluminescence technique. Results were compared between the groups, and p values of <0.05 were considered as statistically significant.</p> </sec> <sec id="aos12398-sec-0003" sec-type="section"> <title>Results</title> <p>No significant differences were found between the groups with respect to age (p = 0.41) and sex (p = 0.98). Plasma vitamin D levels of the subjects with SAC (median 8.03 ng/ml, range 3.00–17.97 ng/ml) were significantly lower than the control group (median 10.52 ng/ml, range 3.30–25.92 ng/ml) (p = 0.007). Serum total IgE levels of patients with SAC (median 48.65 IU/ml, range 1.77–812.00 IU/ml) were significantly higher when compared to the control group (median 32.49 IU/ml, range 0.14–104.60 IU/ml) (p = 0.003).</p> </sec> <sec id="aos12398-sec-0004" sec-type="section"> <title>Conclusions</title> <p>We found lower plasma vitamin D levels and higher serum total IgE levels in patients with SAC.</p> </sec> </abstract>