Glistening in glaucomatous eyes: visual performances and risk factors. (7th October 2013)

• Record Type: Journal Article
• Authors: Schweitzer, Cedric; Orignac, Isabelle; Praud, Delphine; Chatoux, Olivier; Colin, Joseph
• Is Part Of: Acta ophthalmologica. Volume 92:Number 6(2014)
• Page Start: 529
• Page End: 534
• Publication Date: 2013-10-07
• Subjects: Ophthalmology -- Periodicals; 617.7005
• DOI: 10.1111/aos.12276
• Languages: English
• ISSNs: 1755-375X

Abstract

<abstract abstract-type="main" id="aos12276-abs-0001"> <title>Abstract</title> <sec id="aos12276-sec-0001" sec-type="section"> <title>Purpose</title> <p>To analyse risk factors and visual performances of glaucomatous eyes with glistening in the intra‐ocular lens (IOL).</p> </sec> <sec id="aos12276-sec-0002" sec-type="section"> <title>Methods</title> <p>Prospective study performed between November 2010 and April 2011 and involving 67 consecutive glaucomatous eyes (47 patients), who previously had a phacoemulsification with a hydrophobic acrylic IOL implanted in the capsular bag. Glistening was classified in three groups of severity grade: G0 (<50 microvacuoles per mm<sup>2</sup>), G1 (50–150 microvacuoles per mm<sup>2</sup>), and G2 (>150 microvacuoles per mm<sup>2</sup>). All eyes underwent a best‐corrected visual acuity evaluation (BCVA, LogMAR scale), a complete clinical examination, a visual field test, a contrast sensitivity evaluation and a wavefront analysis of high‐order aberrations (HOAs) using a Shack–Hartmann aberrometer. Eyes with a posterior capsular opacification and a BCVA>0.30 LogMAR were excluded.</p> </sec> <sec id="aos12276-sec-0003" sec-type="section"> <title>Results</title> <p>Twenty six eyes (38.8%) had a grade 0, 12 eyes (17.9%) a grade 1 and 29 eyes (43.3%) a grade 2 of glistening severity grade. The mean follow‐up after cataract surgery was 35.2 ± 24.2 months and was significantly higher for G1 and G2 groups (p < 0.001). A higher number of topical glaucoma medication were associated with a higher glistening severity grade (p < 0.05). G1 and G2 groups had significantly lower mean contrast sensitivity values at high spatial frequencies and significantly higher loss variance (LV) values of the visual field test (p < 0.05). There was no significant difference in mean BCVA between groups (p = 0.455).</p> </sec> <sec id="aos12276-sec-0004" sec-type="section"> <title>Conclusions</title> <p>In glaucomatous eyes, glistening increased with time was associated with the number of topical glaucoma medications daily instilled and altered visual performances. It should be a consideration for glaucoma patients who are more likely to develop glistening within the IOL optic.</p> </sec> </abstract>