ChemInform Abstract: β‐Hydroxy‐γ‐lactones as Nucleophiles in the Nicholas Reaction for the Synthesis of Oxepene Rings. Enantioselective Formal Synthesis of (‐)‐Isolaurepinnacin (I) and (+)‐Rogioloxepane A (II). Issue 35 (2nd September 2014) - Rodriguez‐Lopez, Julio
Abstract The key steps consist of an intermolecular Nicholas reaction with a β‐hydroxy‐γ‐lactone as a nucleophile and a ring closing metathesis reaction.