Catalytic Asymmetric Torgov Cyclization: A Concise Total Synthesis of (+)‐Estrone1. Issue 33 (30th July 2014) - Prévost, Sébastien
Abstract An asymmetric Torgov cyclization, catalyzed by a novel, highly Brønsted acidic dinitro‐substituted disulfonimide, is described. The reaction delivers the Torgov diene and various analogues with excellent yields and enantioselectivity. This method was applied in a very short synthesis of (+)‐estrone.