Transforaminal Epidural Steroid Injections Followed by Mechanical Diagnosis and Therapy to Prevent Surgery for Lumbar Disc Herniation. Issue 7 (7th May 2014)

• Record Type: Journal Article
• Authors: van Helvoirt, Hans; Apeldoorn, Adri T.; Ostelo, Raymond W.; Knol, Dirk L.; Arts, Mark P.; Kamper, Steven J.; van Tulder, Maurits W.
• Is Part Of: Pain medicine. Volume 15:Issue 7(2014)
• Page Start: 1100
• Page End: 1108
• Publication Date: 2014-05-07
• Subjects: Pain -- Periodicals; Pain -- Treatment -- Periodicals; Analgesics -- Periodicals; Pain -- Periodicals; Pain Management -- Periodicals; Douleur -- Périodiques; Douleur -- Traitement -- Périodiques; Analgésiques -- Périodiques; Analgésique; Soulagement de la douleur; Périodique électronique (Descripteur de forme); Ressource Internet (Descripteur de forme); 616.047205
• DOI: 10.1111/pme.12450
• Languages: English
• ISSNs: 1526-2375

Abstract

<abstract abstract-type="main"> <title>Abstract</title> <sec id="pme12450-sec-0001" sec-type="section"> <title>Study Design</title> <p>Prospective cohort study.</p> </sec> <sec id="pme12450-sec-0002" sec-type="section"> <title>Objective</title> <p>To report the clinical course of patients with MRI‐confirmed lumbar disc herniation‐related radicular noncentralizing pain who received transforaminal epidural steroid injections (TESIs) and mechanical diagnosis and therapy (MDT).</p> </sec> <sec id="pme12450-sec-0003" sec-type="section"> <title>Summary of Background Data</title> <p>Noncentralizing symptoms in patients with lumbar disc herniation are associated with poor outcome. Commonly used treatments for these patients include TESIs and MDT. No study has evaluated the outcome of combining both strategies.</p> </sec> <sec id="pme12450-sec-0004" sec-type="section"> <title>Methods</title> <p>Consecutive candidates for herniated lumbar disc surgery with noncentralizing chronic pain were eligible. Patients received TESIs followed by MDT. The primary outcomes were pain severity in the leg, disability (Roland–Morris Disability Questionnaire for Sciatica), and global perceived effect (GPE). Outcomes were measured at baseline, discharge, and 12 months. Linear mixed‐models and McNemar's tests were used to analyze outcome data.</p> </sec> <sec id="pme12450-sec-0005" sec-type="section"> <title>Results</title> <p>Sixty‐nine patients receive TESIs. After TESIs, symptoms were resolved completely in 11 patients (16%). In these patients, symptom resolution was maintained at 12 months. A second subgroup of 32 patients (46%) reported significantly less pain after TESIs and showed centralization with MDT reassessment (significant reductions in leg pain and disability [<italic>P</italic> < 0.001]) and a satisfaction rate of 90% at 12 months. A third subgroup of 11 patients (16%) reported significantly less pain after TESIs but still showed noncentralization with MDT reassessment (significant reductions in leg pain and disability [<italic>P</italic> < 0.05] and a satisfaction rate of 50% at 12 months). A fourth subgroup of 15 patients (22%) did not respond on TESIs and received an operative intervention.</p> </sec> <sec id="pme12450-sec-0006" sec-type="section"> <title>Conclusion</title> <p>The results indicate that a course of TESIs followed by MDT may be able to avoid surgery in a substantial proportion of candidates for herniated lumbar disc surgery.</p> </sec> </abstract>