Beyond weight reduction: Improvements in quality of life after an intensive lifestyle intervention in subjects with severe obesity. (August 2014)

• Record Type: Journal Article
• Authors: Danielsen, Kjersti Karoline; Sundgot-Borgen, Jorunn; Mæhlum, Sverre; Svendsen, Mette
• Is Part Of: Annals of medicine. Volume 46:Number 5(2014)
• Page Start: 273
• Page End: 282
• Publication Date: 2014-08
• Subjects: Medicine -- Periodicals; 610
• DOI: 10.3109/07853890.2013.874660
• Languages: English
• ISSNs: 0785-3890

Abstract

<abstract> <title>Abstract</title> <p> <italic>Introduction.</italic> We examined the effects of 10–14 weeks of inpatient intensive lifestyle intervention (ILI), including a minimum of 90 minutes of adapted physical activity 5 days/week, with regard to changes in quality of life and associations with weight loss in subjects with severe obesity.</p> <p> <italic>Methods.</italic> A total of 100 severely obese subjects (BMI 42.6 ± 5.3 kg/m<sup>2</sup>; 42.7 ± 10.6 years) were included. Quality of life was assessed by Binge Eating Scale, Hospital Anxiety, and Depression Scale, and SF- 36. The ILI group completed the questionnaires at inclusion, after 10–14 weeks and 12 months, and controls at inclusion and after 10–14 weeks.</p> <p> <italic>Results.</italic> Compared to controls, self-reported binge eating (–6.4, <italic>P</italic> < 0.0001), anxiety (–1.7, <italic>P</italic> = 0.005), and depression (–3.0, <italic>P</italic> < 0.0001) were reduced, and physical (8.0, <italic>P</italic> < 0.0001) and mental (7.6, <italic>P</italic> < 0.0001) health increased in the ILI group. After 12 months, reduction in self-reported binge eating (–7.2, <italic>P</italic> < 0.0001) and depression (–3.4, <italic>P</italic> < 0.0001) and increase in physical (8.9, <italic>P</italic> < 0.0001) and mental (3.6, <italic>P</italic> = 0.035) health were maintained. Decreased self-reported binge eating (β = 0.555, <italic>P = </italic> 0.010) and increased physical health (β = –0.554, <italic>P</italic> = 0.003) were associated with weight loss.</p> <p> <italic>Conclusion.</italic> ILI including a high volume of physical activity in subjects with severe obesity improved quality of life by favorable changes in self-reported binge eating, depression, and mental and physical health. Improvements in binge eating and physical health were associated with weight loss.</p> </abstract>