Listeria monocytogenes induces IFNβ expression through an IFI16‐, cGAS‐ and STING‐dependent pathway. (26th June 2014)

• Record Type: Journal Article
• Authors: Hansen, Kathrine; Prabakaran, Thaneas; Laustsen, Anders; Jørgensen, Sofie E; Rahbæk, Stine H; Jensen, Søren B; Nielsen, Rikke; Leber, Jess H; Decker, Thomas; Horan, Kristy A; Jakobsen, Martin R; Paludan, Søren R
• Is Part Of: EMBO journal. Volume 33:Number 15(2014)
• Page Start: 1654
• Page End: 1666
• Publication Date: 2014-06-26
• Subjects: Molecular biology -- Periodicals; 572.805
• DOI: 10.15252/embj.201488029
• Languages: English
• ISSNs: 0261-4189

Abstract

<abstract abstract-type="graphical" xml:lang="en" id="embj201488029-abs-0003"> <title> <x xml:space="preserve">Abstract</x> </title> <p>While bacterium‐derived cyclic‐di‐AMP triggers interferon responses in murine cells, <italic>Listeria monocytogenes</italic>‐infected human myeloid cells utilize an innate immune sensory pathway that directly recognizes bacterial DNA. <boxed-text content-type="graphic" id="embj201488029-blkfxd-0002" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pghwkf9vhz" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>