Echocardiographic Particle Image Velocimetry for the Evaluation of Diastolic Function in Hypertrophic Nonobstructive Cardiomyopathy. Issue 7 (20th December 2013)

• Record Type: Journal Article
• Authors: Prinz, Christian; Lehmann, Roman; Brandao da Silva, Douglas; Jurczak, Barbara; Bitter, Thomas; Faber, Lothar; Horstkotte, Dieter
• Is Part Of: Echocardiography. Volume 31:Issue 7(2014)
• Page Start: 886
• Page End: 894
• Publication Date: 2013-12-20
• Subjects: Echocardiography -- Periodicals; Echocardiography -- Periodicals; 616.1207543
• DOI: 10.1111/echo.12487
• Languages: English
• ISSNs: 0742-2822

Abstract

<abstract abstract-type="main" id="echo12487-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="echo12487-sec-0001" sec-type="section"> <title>Aims</title> <p>To use particle image velocimetry (PIV) echocardiography for the evaluation of diastolic dysfunction (DD) in patients with hypertrophic nonobstructive cardiomyopathy (HNCM).</p> </sec> <sec id="echo12487-sec-0002" sec-type="section"> <title>Methods</title> <p>This study included 50 individuals, thereof 30 patients with DD due to HNCM and 20 healthy individuals who served as controls. HNCM patients were divided into 3 groups according to DD severity. All subjects underwent clinical assessment, exercise testing, and standard as well as PIV echocardiography.</p> </sec> <sec id="echo12487-sec-0003" sec-type="section"> <title>Results</title> <p>Energy dissipation was higher in DD patients than in the control group. The severity of flow pattern disturbance corresponded to the degree of DD. In a subgroup of 20 HNCM patients we found significant correlations between invasive measured left ventricular end‐diastolic pressure and noninvasive PIV parameters for intraventricular pressure differences and filling. Inter‐observer variability (mean difference ± 1.96 SD) for all tested PIV measurements was good.</p> </sec> <sec id="echo12487-sec-0004" sec-type="section"> <title>Conclusion</title> <p>According to DD severity, patients with HNCM have disturbed intraventricular flow and reduced intraventricular pressure differences, consistent with a reduced intraventricular suction. PIV echocardiography appears to be feasible for detailed analysis of ventricular vortex flow in DD conditions. Further research using PIV echocardiography in different cardiac pathologies seems warranted.</p> </sec> </abstract>