Effect of phacoemulsification on trabeculectomy function. (17th December 2013)

• Record Type: Journal Article
• Authors: Nguyen, Dan Q; Niyadurupola, Nuwan; Tapp, Robyn J; O'Connell, Rachael A; Coote, Michael A; Crowston, Jonathan G
• Is Part Of: Clinical & experimental ophthalmology. Volume 42:Number 5(2014)
• Page Start: 433
• Page End: 439
• Publication Date: 2013-12-17
• Subjects: Ophthalmology -- Periodicals; 617.7
• DOI: 10.1111/ceo.12254
• Languages: English
• ISSNs: 1442-6404

Abstract

<abstract abstract-type="main"> <title>Abstract</title> <sec id="ceo12254-sec-0001" sec-type="section"> <title>Background</title> <p>To evaluate the effect of phacoemulsification on trabeculectomy function.</p> </sec> <sec id="ceo12254-sec-0002" sec-type="section"> <title>Design</title> <p>Retrospective case–control study.</p> </sec> <sec id="ceo12254-sec-0003" sec-type="section"> <title>Participants</title> <p>Forty‐eight patients who underwent trabeculectomy surgery and had at least 2 years of follow up.</p> </sec> <sec id="ceo12254-sec-0004" sec-type="section"> <title>Methods</title> <p>Patients were classified into two groups: patients who had phacoemulsification subsequent to trabeculectomy (Trab_phaco, <italic>n</italic> = 18) and patients who were pseudophakic for greater than 6 months preceding their trabeculectomy (Phaco_trab, <italic>n</italic> = 30). Groups were matched for length of follow up of 2 years from time of trabeculectomy.</p> </sec> <sec id="ceo12254-sec-0005" sec-type="section"> <title>Main Outcome Measures</title> <p>The primary outcome measures were target intraocular pressure of criteria A, ≤12 mmHg; B, ≤15 mmHg; C, ≤18 mmHg with or without additional topical treatment. A separate measure for bleb function failure was also used; with failure defined as the need for additional topical antiglaucoma therapy or surgical intervention to achieve control of intraocular pressure.</p> </sec> <sec id="ceo12254-sec-0006" sec-type="section"> <title>Results</title> <p>There was no significant difference in achieving each intraocular pressure criterion between groups (12 months, <italic>P</italic> = 1.0; 24 months, <italic>P</italic> = 0.330). In the first 12 months, significantly more trabeculectomies in the Trab_phaco group failed, requiring additional intervention to control the IOP (39%) compared with the Phaco_trab (10%) group (<italic>P</italic> = 0.028). Although this trend continued at 24 months, there were no significant differences in failure rates (<italic>P</italic> = 0.522).</p> </sec> <sec id="ceo12254-sec-0007" sec-type="section"> <title>Conclusions</title> <p>Phacoemulsification performed after trabeculectomy significantly increased rates of bleb failure in the following 12 months but not at 24 months.</p> </sec> </abstract>