Priming for health: gut microbiota acquired in early life regulates physiology, brain and behaviour. (17th May 2014)

• Record Type: Journal Article
• Authors: Clarke, G; O'Mahony, SM; Dinan, TG; Cryan, JF
• Is Part Of: Acta pædiatrica. Volume 103:Number 8(2014:Aug.)
• Page Start: 812
• Page End: 819
• Publication Date: 2014-05-17
• Subjects: Pediatrics -- Periodicals; Pediatrics; 618.92
• DOI: 10.1111/apa.12674
• Languages: English
• ISSNs: 0803-5253

Abstract

<abstract abstract-type="main" id="apa12674-abs-0001"> <title>Abstract</title> <sec id="apa12674-sec-0001" sec-type="section"> <p>The infant gut microbiome is dynamic, and radical shifts in composition occur during the first 3 years of life. Disruption of these developmental patterns, and the impact of the microbial composition of our gut on brain and behaviour, has attracted much recent attention. Integrating these observations is an important new research frontier.</p> </sec> <sec id="apa12674-sec-0002" sec-type="section"> <title>Conclusion</title> <p>Early‐life perturbations of the developing gut microbiota can impact on the central nervous system and potentially lead to adverse mental health outcomes.</p> </sec> </abstract>