Can we use electrocochleography as a clinical tool in the diagnosis of Meniere's disease during the early symptomatic period?. (August 2014)

• Record Type: Journal Article
• Authors: Oh, Kyoung Ho; Kim, Kang-Woo; Chang, Jiwon; Jun, Hyun-Su; Kwon, Eun Ha; Choi, Jeong-Yoon; Im, Gi Jung; Chae, Sung Won; Jung, Hak Hyun; Choi, June
• Is Part Of: Acta oto-laryngologica. Volume 134:Number 8(2014)
• Page Start: 771
• Page End: 775
• Publication Date: 2014-08
• Subjects: Otolaryngology -- Periodicals; Ear -- Diseases -- Periodicals; Throat -- Diseases -- Periodicals; Otolaryngology -- Electronic Resources; Otorhinolaryngologic Diseases; 617.8
• DOI: 10.3109/00016489.2014.907500
• Languages: English
• ISSNs: 0001-6489

Abstract

<abstract> <title>Abstract</title> <p> <italic>Conclusion:</italic> Our results indicate that electrocochleography (ECoG) has limited value in diagnosing Meniere's disease during the early symptomatic period. <italic>Objective:</italic> We hypothesized that if endolymphatic hydrops is a cause of Meniere's disease, ECoG results obtained in normal subjects would differ from those obtained during the early symptomatic period of Meniere's disease. We aimed to investigate the usefulness of ECoG in the diagnosis of Meniere's disease during the early symptomatic period. <italic>Methods:</italic> Extratympanic ECoG was used to evaluate 60 patients in a Meniere's group (17 men, 43 women; mean age 43.6 years, range 19–62 years) and 30 controls (11 men, 19 women; mean age 43.5 years, range 21–63 years). The summating potential/action potential (SP/AP) amplitude ratio and SP/AP area ratio were compared between the groups. <italic>Results:</italic> Statistically significant differences were not demonstrated in the SP/AP amplitude ratio between the definite Meniere's, probable Meniere's, overall Meniere's, or control groups (0.35 ± 0.02, 0.30 ± 0.03, 0.33 ± 0.02, and 0.30 ± 0.01, respectively). Additionally, statistically significant differences were not indicated in the mean SP/AP area ratio between the definite Meniere's, probable Meniere's, overall Meniere's, or control groups (5.18 ± 0.98, 4.78 ± 0.21, 4.01 ± 0.78, and 3.72 ± 0.66, respectively).</p> </abstract>