Obesity and mortality: are the risks declining? Evidence from multiple prospective studies in the United States. Issue 8 (9th June 2014)

• Record Type: Journal Article
• Authors: Mehta, T.; Fontaine, K. R.; Keith, S. W.; Bangalore, S. S.; de los Campos, G.; Bartolucci, A.; Pajewski, N. M.; Allison, D. B.
• Is Part Of: Obesity reviews. Volume 15:Issue 8(2014)
• Page Start: 619
• Page End: 629
• Publication Date: 2014-06-09
• Subjects: Obesity -- Periodicals; 616.398005
• DOI: 10.1111/obr.12191
• Languages: English
• ISSNs: 1467-7881

Abstract

<abstract abstract-type="main"> <title>Summary</title> <p>We evaluated whether the obesity‐associated years of life lost (YLL) have decreased over calendar time. We implemented a meta‐analysis including only studies with two or more serial body mass index (BMI) assessments at different calendar years. For each BMI category (normal weight: BMI 18.5 to <25 [reference]; overweight: BMI 25 to <30; grade 1 obesity: BMI 30 to <35; and grade 2–3 obesity: BMI ≥ 35), we estimated the YLL change between 1970 and 1990. Because of low sample sizes for African–American, results are reported on Caucasian. Among men aged ≤60 years YLL for grade 1 obesity increased by 0.72 years (<italic>P</italic> < 0.001) and by 1.02 years (<italic>P</italic> = 0.01) for grade 2–3 obesity. For men aged >60, YLL for grade 1 obesity decreased by 1.02 years (<italic>P</italic> < 0.001) and increased by 0.63 years for grade 2–3 obesity (<italic>P</italic> = 0.63). Among women aged ≤60, YLL for grade 1 obesity decreased by 4.21 years (<italic>P</italic> < 0.001) and by 4.97 years (<italic>P</italic> < 0.001) for grade 2–3 obesity. In women aged >60, YLL for grade 1 obesity decreased by 3.98 years (<italic>P</italic> < 0.001) and by 2.64 years (<italic>P</italic> = 0.001) for grade 2–3 obesity. Grade 1 obesity's association with decreased longevity has reduced for older Caucasian men. For Caucasian women, there is evidence of a decline in the obesity YLL association across all ages.</p> </abstract>