Clinical Experience of Modified Diffusion‐Weighted Imaging Protocol for Lesion Detection in Transient Global Amnesia: An 8‐Year Large‐Scale Clinical Study. Issue 4 (2nd April 2013)

• Record Type: Journal Article
• Authors: Kim, Jungeun; Kwon, Yooseok; Yang, Youngsoon; Jang, Il Mi; Chang, YoungHee; Park, Young Ho; Jang, Jae Won; Kim, Jae Hyoung; Kim, SangYun
• Is Part Of: Journal of neuroimaging. Volume 24:Issue 4(2014)
• Page Start: 331
• Page End: 337
• Publication Date: 2013-04-02
• Subjects: Diagnostic imaging -- Periodicals; Nervous system -- Diseases -- Diagnosis -- Periodicals; Imagerie pour le diagnostic -- Périodiques; Système nerveux -- Maladies -- Diagnostic -- Périodiques; Imagerie médicale; Neuroimagerie; Neurologie; Système nerveux; Périodique électronique (Descripteur de forme); Ressource Internet (Descripteur de forme); 616.804754
• DOI: 10.1111/jon.12021
• Languages: English
• ISSNs: 1051-2284

Abstract

<abstract abstract-type="main"> <title>ABSTRACT</title> <sec id="jon12021-sec-0010" sec-type="section"> <title>BACKGROUND AND PURPOSE</title> <p>The detection rate of typical transient global amnesia (TGA) lesions on diffusion‐weighted imaging (DWI) can be improved, up to 85% with optimal DWI parameters and imaging time. There is limited evidence that these findings are similar to those observed in large‐scale consecutive patients with TGA in clinical practice.</p> </sec> <sec id="jon12021-sec-0020" sec-type="section"> <title>METHODS</title> <p>Patients with clinically diagnosed TGA underwent magnetic resonance imaging studies, consecutively, with three sets of DWI parameters (standard clinical DWI protocols, the TGA DWI protocol I and the TGA DWI protocol II) in which the resolution, slice thickness, and the time interval between symptom onset of DWI were varied over an 8‐year period.</p> </sec> <sec id="jon12021-sec-0030" sec-type="section"> <title>RESULTS</title> <p>TGA lesion detection rates were up to 88% with a modified TGA DWI protocol. The lesion detection rate was the highest using TGA DWI protocol I, with <italic>b</italic> = 3, 000 s/mm<sup>2</sup>, a slice thickness of 3 mm, and performed on the third day after symptom onset, and TGA DWI protocol II, with <italic>b</italic> = 2, 000 s/mm<sup>2</sup> and a slice thickness of 2 mm.</p> </sec> <sec id="jon12021-sec-0040" sec-type="section"> <title>CONCLUSIONS</title> <p>A modified TGA DWI protocols for detecting TGA lesions are useful in large‐scale clinical practice for confirming the diagnosis of TGA patients with clinical findings.</p> </sec> </abstract>