Haemolytic–uraemic syndrome with bacteraemia caused by a new hybrid Escherichia coli pathotype. Issue 4 (27th May 2014)

• Record Type: Journal Article
• Authors: Mariani‐Kurkdjian, P.; Lemaître, C.; Bidet, P.; Perez, D.; Boggini, L.; Kwon, T.; Bonacorsi, S.
• Is Part Of: New microbes and new infections. Volume 2:Issue 4(2014)
• Page Start: 127
• Page End: 131
• Publication Date: 2014-05-27
• Subjects: Medical microbiology -- Periodicals; Communicable diseases -- Periodicals; Infection -- Periodicals; Microbiology -- Periodicals; Communicable Diseases -- Periodicals; Infection -- Periodicals; 616.9041
• DOI: 10.1002/nmi2.49
• Languages: English
• ISSNs: 2052-2975

Abstract

<abstract abstract-type="main" id="nmi249-abs-0001"> <title>Abstract</title> <p>We describe a new atypical Shiga‐toxin‐producing <italic>Escherichia coli</italic> (STEC) responsible for a severe episode of haemolytic–uraemic syndrome in an adult with a relapse associated with bacteraemia. This STECs train of serotype O80:H2 harboured <italic>stx2c</italic> and <italic>stx2d</italic> gene subtypes, the rare <italic>eae</italic> ξ variant and a ColV plasmid with a conserved virulence plasmidic region involved in virulence of human and avian extraintestinal pathogenic <italic>E. coli</italic>. This atypical hybrid pathotype, which represents a new threat, is a further demonstration that STEC may be a recipient for extraintestinal virulence factors and raises again the question of antibiotic therapy during STEC infection.</p> </abstract>