A Probe for the Selective and Parts‐per‐Billion‐Level Detection of Copper(II) and Mercury(II) using a Micellar Medium and Its Utility in Cell Imaging. Issue 7 (6th May 2014)

• Record Type: Journal Article
• Authors: Kumari, Namita; Jha, Satadru; Misra, Santosh K.; Bhattacharya, Santanu
• Is Part Of: ChemPlusChem. Volume 79:Issue 7(2014:Jul.)
• Page Start: 1059
• Page End: 1064
• Publication Date: 2014-05-06
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1002/cplu.201402016
• Languages: English
• ISSNs: 2192-6506

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>A novel colorimetric probe <bold>1</bold> based on the picolyl moiety has been designed and synthesized. Probe <bold>1</bold> is composed of a pyrene and a bispicolyl amine (BPA) unit, in which the BPA moiety acts as a binding unit and the binding phenomenon is sensed from the changes in the signaling subunit. The probe detects Cu²⁺ specifically in water and both Cu²⁺ and Hg²⁺ efficiently in neutral Brij‐58 micellar media. The probe shows a color change visible to the naked eye upon addition of metal ions. Notably, in a micellar medium, probe <bold>1</bold> can detect both the Cu²⁺ and Hg²⁺ ions even at parts‐per‐billion levels. Furthermore, the probe shows ratiometric detection of both the metal ions making the sensing quantitative. The two metal ions could be discriminated both visibly under a UV lamp and with the use of fluorescence spectroscopy. The probe could be also used in biological cell lines for the detection of both Hg²⁺ and Cu²⁺ ions.</p> </abstract>