Rapidly progressing primary splenic angiosarcoma with fatal hemorrhagic event. (August 2014)

• Record Type: Journal Article
• Authors: Cho, Eun Ae; Choi, Won-Young; Kim, Seung-Hun; Hong, Ji-Yun; Jung, Sung-Hoon; Kim, Min-Jee; Hwang, Jun-Eul; Bae, Woo-Kyun; Shim, Hyun-Jeong; Lee, Kyung-Hwa; Cho, Sang-Hee; Chung, Ik-Joo
• Is Part Of: Journal of chemotherapy. Volume 26:Number 4(2014:Aug.)
• Page Start: 248
• Page End: 252
• Publication Date: 2014-08
• Subjects: Chemotherapy -- Periodicals; Drug Therapy -- Periodicals; 615.58
• DOI: 10.1179/1973947813Y.0000000146
• Languages: English
• ISSNs: 1120-009X

Abstract

<abstract> <title> <x content-type="archive" xml:space="preserve">Abstract</x> </title> <p>Primary angiosarcoma of the spleen is an extremely rare malignancy. Splenic angiosarcoma is difficult to diagnose, and treatment is often challenging. The prognosis is dismal, with a mean survival of less than 1 year. Currently, no standard treatment methods have been established. Anecdotal reports suggest that early diagnosis and prompt splenectomy followed by cytotoxic chemotherapy can be effective treatment modalities. We report a case of rapidly progressing primary splenic angiosarcoma with multiple liver and bone metastases and a fatal hemorrhagic outcome.</p> </abstract>