Composite Material Based on Macroporous Polyaniline and Osmium Redox Complex for Biosensor Development. Issue 7 (11th June 2014)

• Record Type: Journal Article
• Authors: Antiochia, Riccarda; Mazzei, Franco; Gorton, Lo; Leech, Dónal; Favero, Gabriele
• Is Part Of: Electroanalysis. Volume 26:Issue 7(2014:Jul.)
• Page Start: 1623
• Page End: 1630
• Publication Date: 2014-06-11
• Subjects: Electrochemical analysis -- Periodicals; Chemistry, Analytical -- Periodicals; Electrochemistry -- Periodicals; 543.4
• DOI: 10.1002/elan.201400021
• Languages: English
• ISSNs: 1040-0397

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>Here the feasibility of layers based on the conducting polymer polyaniline (PANI) as component of glucose biosensors using glucose oxidase (GOx) as enzyme and [Os(bpy)₂(4‐aminomethylpyridine)Cl]PF₆ (OsCmplx) as electrochemical mediator, is evaluated. Particularly, PANI was employed to obtain a nanostructured macroporous material (m‐PANI) around polystyrene nanoparticles taken as template and the mediator was co‐immobilized during the polymerizing procedure. The GOx biosensor based on OsCmplx modified m‐PANI provides a linear response to glucose concentration in the range 5 up to 65 mM with a sensitivity of 3.54 µA/mM/cm² (on a projected geometric area=0.07 cm²), an <italic>LOD</italic> of 0.8 mM and a good precision (%<italic>RSD</italic>≤7, <italic>n</italic>=5); the biosensor is stable showing a decrease of 10% to the value of the sensitivity after 15 days of use and of about 50% after 40 days.</p> </abstract>