Catalytic Asymmetric α‐Hydroxyamination of Carbonyls with N‐Hydroxycarbamates Becomes Greener. Issue 7 (2nd June 2014) - Yu, Chenguang
Abstract The power of two: A highly enantio‐ and regioselective aminocatalytic and Lewis acid catalyzed α‐hydroxyamination of β‐keto esters and 1, 3‐diketones with N‐hydroxycarbamates is realized in "one‐pot" under aerobic conditions. The powerful dual catalysis strategy opens opportunities for developing new efficient organic transformations. Cbz=Benzyloxycarbonyl, Boc=tert‐butoxycarbonyl.