Two novel alleles HLA‐DRB1*11:150 and HLA‐DRB1*14:145 identified in Saudi individuals. (12th June 2014)

• Record Type: Journal Article
• Authors: Fakhoury, H. A.; Cereb, N.; Jawdat, D.; Al Jumah, M.; Alaskar, A. S.; Hajeer, A. H.
• Is Part Of: International journal of immunogenetics. Volume 41:Number 4(2014:Aug.)
• Page Start: 340
• Page End: 341
• Publication Date: 2014-06-12
• Subjects: Immunogenetics -- Periodicals; 571.9648
• DOI: 10.1111/iji.12133
• Languages: English
• ISSNs: 1744-3121

Abstract

<abstract abstract-type="main" id="iji12133-abs-0001"> <title>Summary</title> <p>Two new HLA‐ DRB1 alleles were identified by sequence‐based typing method (SBT) in 1100 participants in the Saudi Stem Cell Donor Registry. HLA‐DRB1*11:150 differs from HLA‐DRB1*11:01:01G by a single C to A substitution at nucleotide position 5580 in exon 2, resulting in an amino acid change from alanine to glutamic acid at position 74. HLA‐DRB1*14:145 differs from HLA‐DRB1*14:04 by a C to G substitution at nucleotide position 5511 in exon 2, resulting in an amino acid change from threonine to arginine at position 51.</p> </abstract>