Dimensions of the endometrial cavity and intrauterine device expulsion or removal for displacement: a nested case–control study. (11th February 2014)

• Record Type: Journal Article
• Authors: Liang, H; Li, L; Yuan, W; Zou, Y; Gao, E‐S; Duffy, JMN; Wu, S‐C
• Is Part Of: BJOG. Volume 121:Number 8(2014:Aug.)
• Page Start: 997
• Page End: 1004
• Publication Date: 2014-02-11
• Subjects: Obstetrics -- Periodicals; Gynecology -- Periodicals; 618
• DOI: 10.1111/1471-0528.12619
• Languages: English
• ISSNs: 1470-0328

Abstract

<abstract abstract-type="main" id="bjo12619-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="bjo12619-sec-0001" sec-type="section"> <title>Objective</title> <p>To evaluate the effect of the dimensions of the uterine cavity in relation to the expulsion, or removal for displacement, of intrauterine devices (IUDs) MLCu375 and TCu380A.</p> </sec> <sec id="bjo12619-sec-0002" sec-type="section"> <title>Design</title> <p>A case–control study nested in a multicentre clinical trial.</p> </sec> <sec id="bjo12619-sec-0003" sec-type="section"> <title>Setting</title> <p>Eighteen family planning clinics in China.</p> </sec> <sec id="bjo12619-sec-0004" sec-type="section"> <title>Population</title> <p>Forty‐eight pairs of TCu380A users and 118 pairs of MLCu375 users.</p> </sec> <sec id="bjo12619-sec-0005" sec-type="section"> <title>Methods</title> <p>The women were classified as cases if IUD expulsion or displacement occurred during the first year of follow‐up after insertion. One control was randomly selected for each case matched by IUD model, centre, age, service provider for insertion, and date of insertion. Axial length of the uterine cavity (LUC) and the largest transverse diameter of the coronal section of the uterine cavity (LTD) were measured using abdominal ultrasound. We used multivariate conditional logistic regressions to estimate the adjusted odds ratios (aORs) of expulsions or displacements among women with different sizes of uterine cavity according to the quartile of LUC and LTD, respectively.</p> </sec> <sec id="bjo12619-sec-0006" sec-type="section"> <title>Results</title> <p>Among MLCu375 users, women with LTD ≥ 27 mm had a higher risk of expulsion or displacement (aOR 2.40; 95% confidence interval, 95% CI, 1.02–5.63), after adjusting for the volume of menstrual flow, dysmenorrhoea, parity, uterine position, MLCu375 type, and LUC. Among TCu380A users, the association between LTD ≥ 37 mm and expulsion or displacement (aOR 4.98; 95% CI 1.01–22.49) was statistically significant, after adjusting for LUC and potential confounding factors.</p> </sec> <sec id="bjo12619-sec-0007" sec-type="section"> <title>Conclusion</title> <p>Our study suggests that LTD should be considered when making the decision of which IUD model to use.</p> </sec> </abstract>