Tuberculosis in pediatric oncology and bone marrow transplantation patients. Issue 8 (20th February 2014)

• Record Type: Journal Article
• Authors: Cruz, Andrea T.; Airewele, Gladstone; Starke, Jeffrey R.
• Is Part Of: Pediatric blood & cancer. Volume 61:Issue 8(2014:Aug.)
• Page Start: 1484
• Page End: 1485
• Publication Date: 2014-02-20
• Subjects: Tumors in children -- Periodicals; Blood -- Diseases -- Periodicals; Cancer in children -- Periodicals; 618.92
• DOI: 10.1002/pbc.24985
• Languages: English
• ISSNs: 1545-5009

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="pbc24985-sec-0001" sec-type="section"> <p>Five children with malignancies (3 hematologic, 1 medulloblastoma, 1 hepatoblastoma) and one bone marrow transplant patient were treated for tuberculosis over a 30‐year period. Three had pulmonary disease, 3 disseminated tuberculosis, and 1 had scrofula. Four of five had positive tuberculin skin tests, cultures were positive in 5/6 children. One child died of disseminated TB after engraftment, and one child had hepatotoxicity likely related to tuberculosis therapy. All cases were potentially preventable had they been screened due to established risk factors of foreign birth (4/6) or parental foreign birth (2/6). All children should be screened for latent tuberculosis before chemotherapy. Pediatr Blood Cancer 2014; 61:1484–1485. © 2014 Wiley Periodicals, Inc.</p> </sec> </abstract>