Dedifferentiated laryngeal chondrosarcoma: Combined morphologic and functional imaging with positron‐emission tomography/magnetic resonance imaging. (18th December 2013)

• Record Type: Journal Article
• Authors: Purohit, Bela S.; Dulguerov, Pavel; Burkhardt, Karim; Becker, Minerva
• Is Part Of: Laryngoscope. Volume 124:Number 7(2014:Jul.)
• Page Start: E274
• Page End: E277
• Publication Date: 2013-12-18
• Subjects: Otolaryngology -- Periodicals; 617.51005
• DOI: 10.1002/lary.24518
• Languages: English
• ISSNs: 0023-852X

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="lary24518-sec-0025" sec-type="section"> <p>Chondrosarcoma of the larynx is a rare, low‐grade malignancy in terms of histology and clinical behavior. We present an unusual case of laryngeal chondrosarcoma, which developed a large dedifferentiated component on recurrence after primary surgery. The diagnosis of dedifferentiation was suggested in view of the morphological and metabolic findings on hybrid positron‐emission tomography/magnetic resonance imaging (PET/MRI) and was subsequently confirmed surgically. Whole‐organ, slice‐by‐slice radiologic–histologic correlation revealed excellent delineation of the well‐differentiated and dedifferentiated tumor components with PET/MRI. PET/MRI can provide additional functional information to supplement the morphological mapping and histopathology of these tumors.</p> </sec> <sec id="lary24518-sec-0026" sec-type="section"> <p> <italic>Laryngoscope</italic>, 124:E274–E277, 2014</p> </sec> </abstract>