Clinical performance of contrast enhanced abdominal pediatric MRI with fast combined parallel imaging compressed sensing reconstruction. Issue 1 (11th October 2013)

• Record Type: Journal Article
• Authors: Zhang, Tao; Chowdhury, Shilpy; Lustig, Michael; Barth, Richard A.; Alley, Marcus T.; Grafendorfer, Thomas; Calderon, Paul D.; Robb, Fraser J.L.; Pauly, John M.; Vasanawala, Shreyas S.
• Is Part Of: Journal of magnetic resonance imaging. Volume 40:Issue 1(2014)
• Page Start: 13
• Page End: 25
• Publication Date: 2013-10-11
• Subjects: Magnetic resonance imaging -- Periodicals; 616
• DOI: 10.1002/jmri.24333
• Languages: English
• ISSNs: 1053-1807

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="jmri24333-sec-0001" sec-type="section"> <title>Purpose</title> <p>To deploy clinically, a combined parallel imaging compressed sensing method with coil compression that achieves a rapid image reconstruction, and assess its clinical performance in contrast‐enhanced abdominal pediatric MRI.</p> </sec> <sec id="jmri24333-sec-0002" sec-type="section"> <title>Materials and Methods</title> <p>With Institutional Review Board approval and informed patient consent/assent, 29 consecutive pediatric patients were recruited. Dynamic contrast‐enhanced MRI was acquired on a 3 Tesla scanner using a dedicated 32‐channel pediatric coil and a three‐dimensional SPGR sequence, with pseudo‐random undersampling at a high acceleration (R = 7.2). Undersampled data were reconstructed with three methods: a traditional parallel imaging method and a combined parallel imaging compressed sensing method with and without coil compression. The three sets of images were evaluated independently and blindly by two radiologists at one siting, for overall image quality and delineation of anatomical structures. Wilcoxon tests were performed to test the hypothesis that there was no significant difference in the evaluations, and interobserver agreement was analyzed.</p> </sec> <sec id="jmri24333-sec-0003" sec-type="section"> <title>Results</title> <p>Fast reconstruction with coil compression did not deteriorate image quality. The mean score of structural delineation of the fast reconstruction was 4.1 on a 5‐point scale, significantly better (<italic>P</italic> < 0.05) than traditional parallel imaging (mean score 3.1). Fair to substantial interobserver agreement was reached in structural delineation assessment.</p> </sec> <sec id="jmri24333-sec-0004" sec-type="section"> <title>Conclusion</title> <p>A fast combined parallel imaging compressed sensing method is feasible in a pediatric clinical setting. Preliminary results suggest it may improve structural delineation over parallel imaging. <bold>J. Magn. Reson. Imaging 2014;40:13–25</bold>. © <bold>2013 Wiley Periodicals, Inc</bold>.</p> </sec> </abstract>