Quantifying Mitotic Chromosome Dynamics and Positioning. Issue 10 (October 2014)

• Record Type: Journal Article
• Authors: Bissonette, Samantha; Stumpff, Jason
• Is Part Of: Journal of cellular physiology. Volume 229:Issue 10(2014:Oct.)
• Page Start: 1301
• Page End: 1305
• Publication Date: 2014-10
• Subjects: Physiology -- Periodicals; Cell physiology -- Periodicals; 571.6
• DOI: 10.1002/jcp.24634
• Languages: English
• ISSNs: 0021-9541

Abstract

<abstract abstract-type="main" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="jcp24634-sec-0001" sec-type="section"> <p>The proper organization and segregation of chromosomes during cell division is essential to the preservation of genomic integrity. To understand the mechanisms that spatially control the arrangement and dynamics of mitotic chromosomes requires imaging assays to quantitatively resolve their positions and movements. Here, we will discuss analytical approaches to investigate the position‐dependent control of mitotic chromosomes in cultured cells. These methods can be used to dissect the specific contributions of mitotic proteins to the molecular control of chromosome dynamics. J. Cell. Physiol. 229: 1301–1305, 2014. © 2014 Wiley Periodicals, Inc.</p> </sec> </abstract>