Palladium‐Catalyzed Intramolecular Reductive Cross‐Coupling of Csp2Csp3 Bond Formation. Issue 27 (28th May 2014)

• Record Type: Journal Article
• Authors: Liu, Hui; Wei, Jianpeng; Qiao, Zongjun; Fu, Yana; Jiang, Xuefeng
• Is Part Of: Chemistry. Volume 20:Issue 27(2014)
• Page Start: 8308
• Page End: 8313
• Publication Date: 2014-05-28
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.201403093
• Languages: English
• ISSNs: 0947-6539

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>A Pd‐catalyzed efficient reductive cross‐coupling reaction without metallic reductant to construct a Csp²Csp³ bond has been reported. A Pd^IV complex was proposed to be a key intermediate, which subsequently went through double oxidative addition and double reductive elimination to produce the cross‐coupling products by involving Pd^0/II/IV in one transformation. The oxidative addition from Pd^II to Pd^IV was partially demonstrated to be a radical process by self‐oxidation of substrate without additional oxidants. Furthermore, the solvent was proved to be the reductant for this transformation through XPS analysis.</p> </abstract>