Epithelial regeneration and cancer: news from the Src front. (22nd May 2014)

• Record Type: Journal Article
• Authors: Sousa‐Victor, Pedro; Jasper, Heinrich
• Is Part Of: EMBO journal. Volume 33:Number 13(2014)
• Page Start: 1423
• Page End: 1424
• Publication Date: 2014-05-22
• Subjects: Molecular biology -- Periodicals; 572.805
• DOI: 10.15252/embj.201488815
• Languages: English
• ISSNs: 0261-4189

Abstract

<abstract abstract-type="main" id="embj201488815-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <p content-type="executiveSummary">Src family kinases (SFKs) have long been implicated in tumorigenesis, but the exact requirement for individual kinase members, and their specific spatially and temporally defined roles in the maintenance of epithelial homeostasis remained unclear. A study by Cordero <italic>et al</italic> (<xref ref-type="link" rid="embj201488815-bib-0003">2014</xref>) now combines the strengths of <italic>Drosophila</italic> and mouse models for intestinal epithelial regeneration to characterize the role of individual SFKs in epithelial stem cells, tissue regeneration, and tumorigenesis.</p> </abstract>