Direct Allylation of In Situ Generated Aldehyde Acyl Anions by Synergistic NHC and Palladium Catalysis1. (21st May 2014)

• Record Type: Journal Article
• Authors: Ahire, Milind M.; Mhaske, Santosh B.
• Is Part Of: Angewandte Chemie. Volume 126:Number 27(2014)
• Page Start: 7158
• Page End: 7162
• Publication Date: 2014-05-21
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/ange.201400623
• Languages: English
• ISSNs: 0044-8249

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>The direct regioselective allylation of in situ generated aldehyde acyl anions has been achieved by synergistic NHC and Pd catalysis. It provides an efficient access to valuable β, γ‐unsaturated ketones under mild reaction conditions starting from easily accessible allylic carbonates and aldehydes without any preactivation. The synergistic catalysis method demonstrated herein adds a new dimension to the area of metal‐mediated C allylation.</p> </abstract>