The effects of mild-to-severe retinopathy of prematurity on the development of refractive errors and strabismus. (June 2014)

• Record Type: Journal Article
• Authors: Gursoy, Huseyin; Basmak, Hikmet; Bilgin, Burak; Erol, Nazmiye; Colak, Ertugrul
• Is Part Of: Strabismus. Volume 22:Number 2(2014:Jun.)
• Page Start: 68
• Page End: 73
• Publication Date: 2014-06
• Subjects: Strabismus -- Periodicals; Neurophysiology -- Periodicals; 617.762
• DOI: 10.3109/09273972.2014.904899
• Languages: English
• ISSNs: 0927-3972

Abstract

<abstract> <title>Abstract</title> <p> <italic>Purpose</italic>: To investigate the effects of mild-to-severe retinopathy of prematurity (ROP) on refractive state and the incidence of strabismus.</p> <p> <italic>Materials and methods</italic>: Infants born ≤32 weeks of gestation were prospectively evaluated. Inclusion criteria were a follow-up of at least 6 months and at least stage 1 ROP. Group 1 included stage 1 ROP cases. Cases with stage 2 or 3 ROP without indication for treatment formed the second group. Group 3 included cases who received treatment for ROP. Logistic regression, adjusted for birth weight and gestational age, and multiple comparison tests were used to compare outcomes among groups.</p> <p> <italic>Results</italic>: The mean follow-up time was 20.9 ± 6.6 months. In the first (<italic>n</italic> = 21), second (<italic>n</italic> = 22), and third groups (<italic>n</italic> = 23), the right spherical equivalents (SE) were 1.17 ± 1.33, −0.18 ± 3.09, and −1.08 ± 4.05 diopters, and the left SEs were 1.23 ± 1.34, −0.09 ± 3.24, and −1.46 ± 4.02 diopters, respectively (<italic>p</italic> = 0.026 for right SE and 0.008 for left SE). The incidences of anisometropia were 3/21, 4/22, and 11/23 in the first, second, and third groups, respectively (adjusted odds ratios [aOR] for group 3 vs 1 = 5.39, aOR for group 3 vs 2 = 4.06). Strabismus developed in 7/21, 6/22, and 10/23 in groups one, two, and three, respectively (aOR for group 3 vs 1 = 2.06, aOR for group 3 vs 2 = 2.27). Eighteen of these were esotropias.</p> <p> <italic>Conclusions</italic>: Refractive errors and strabismus were associated with mild-to-severe ROP. Esotropia was the most frequent type of strabismus.</p> </abstract>