MRI-guided percutaneous transhepatic cholangiodrainage: feasibility study in a porcine model. (June 2014)

• Record Type: Journal Article
• Authors: Papanikolaou, Ioannis S.; van der Voort, Ivo R.; Chopra, Sascha S.; Seebauer, Christian J.; Rump, Jens; Papas, Maria G.; Triantafyllou, Konstantinos; Baumgart, Daniel C.; Teichgräber, Ulf K.; Wiedenmann, Bertram; Rösch, Thomas
• Is Part Of: Scandinavian journal of gastroenterology. Volume 49:Number 6(2014)
• Page Start: 722
• Page End: 726
• Publication Date: 2014-06
• Subjects: Gastroenterology -- Periodicals; Digestive organs -- Diseases -- Periodicals; 616.33
• DOI: 10.3109/00365521.2014.899619
• Languages: English
• ISSNs: 0036-5521

Abstract

<abstract> <title>Abstract</title> <p> <bold> <italic>Background and study aims.</italic> </bold> MRI-guided procedures combine high-quality imaging with lack of radiation. Percutaneous transhepatic cholangiodrainage under real-time MRI guidance (MRI-PTCD) seems promising, allowing targeted puncture and avoiding multiple blind passes and use of contrast, which are associated with standard PTCD's heaviest complications. <bold><italic>Patients and methods.</italic></bold> Aim of this study was to investigate the feasibility of MRI-PTCD in three outbred piglets. Obstructive cholestasis was induced by common bile duct ligation. Two days later, MRI-PTCD was performed (open MRI, 1.0 Tesla) with prototype MRI-compatible accessories. Visualization was achieved with a balanced steady-state free precession real-time sequence (bSSFP: 0.75 frames/s, TR/TE [ms]: 7.2/3.6; flip angle: 45°; 200 × 200 matrix size; resolution: 1.3 × 1.3 mm<sup>2</sup>, slice thickness: 7 mm). Cannulation of the bile ducts was followed by placement of Yamakawa drainages. <bold><italic>Results.</italic></bold> Twelve punctures were performed (four per animal, 10/12 successful); in 2/10 the bile ducts could not be cannulated. Animal survival was 100% and no significant complications occurred. <bold><italic>Conclusions.</italic></bold> Initial data show that MRI-PTCD can be successfully performed. This may lead to establishment of a new optimized PTCD technique compared to the standard approach under fluoroscopy.</p> </abstract>