A Salen–Co3+ Catalyst for the Hydration of Terminal Alkynes and in Tandem Catalysis with Ru–TsDPEN for the One‐Pot Transformation of Alkynes into Chiral Alcohols. Issue 6 (11th April 2014)

• Record Type: Journal Article
• Authors: Wang, Shoufeng; Miao, Chengxia; Wang, Wenfang; Lei, Ziqiang; Sun, Wei
• Is Part Of: ChemCatChem. Volume 6:Issue 6(2014:Jun.)
• Page Start: 1612
• Page End: 1616
• Publication Date: 2014-04-11
• Subjects: Catalysis -- Periodicals; 541.39505
• DOI: 10.1002/cctc.201400071
• Languages: English
• ISSNs: 1867-3880

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>The cobalt–salen complex (<bold>C1</bold>:[(salen)Co³⁺(OAc)]; salen= <italic>N</italic>, <italic>N</italic>′‐bis(salicylidene)ethylenediamine, OAc=acetate) was found to efficiently promote the hydration of terminal alkynes to give methyl ketones in the presence of the H₂SO₄ cocatalyst. In addition, the one‐pot transformation of alkynes into chiral alcohols through tandem catalysis by catalyst <bold>C1</bold> coupled with a ruthenium–TsDPEN complex (<bold>C3</bold>: [(<italic>R</italic>, <italic>R</italic>‐TsDPEN)Ru²⁺(cymene)]; TsDPEN=(1<italic>R</italic>, 2<italic>R</italic>)<italic>‐N</italic>‐(<italic>p</italic>‐toluenesulfonyl)‐1, 2‐diphenylethylenediamine, cymene=1‐methyl‐4‐(1‐methylethyl)benzene) catalyst was realized with excellent yields and enantioselectivities.</p> </abstract>