Drug Delivery with PEGylated MoS2 Nano‐sheets for Combined Photothermal and Chemotherapy of Cancer. (20th February 2014)

• Record Type: Journal Article
• Authors: Liu, Teng; Wang, Chao; Gu, Xing; Gong, Hua; Cheng, Liang; Shi, Xiaoze; Feng, Liangzhu; Sun, Baoquan; Liu, Zhuang
• Is Part Of: Advanced materials. Volume 26:Number 21(2014)
• Page Start: 3433
• Page End: 3440
• Publication Date: 2014-02-20
• Subjects: Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adma.201305256
• Languages: English
• ISSNs: 0935-9648

Abstract

<abstract abstract-type="graphical" xml:lang="en" id="adma201305256-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>MoS₂ nanosheets</bold> functionalized with poly­ethylene glycol are for the first time used as a multifunctional drug delivery system with high drug loading capacities. Using doxorubicin as the model drug and taking advantages of the strong near‐infrared absorbance of MoS₂, combined photothermal and chemotherapy of cancer is realized in animal experiments, achieving excellent synergistic anti‐tumor effect upon systemic administration. <boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pghgb180b3" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>