A Convenient Protocol for the Synthesis of 2‐(2′‐Hydroxy‐5′‐carboxyphenyl)‐2H‐benzotriazole to Avoid Decarboxylation When Using p‐Hydroxybenzoic Acid as Coupling Component. (6th December 2013)

• Record Type: Journal Article
• Authors: Ma, Wei; Tuo, Tingting; Hu, Jingqiang; Liu, Yong; Zhang, Shufen
• Is Part Of: Journal of heterocyclic chemistry. Volume 51:Number 3(2014)
• Page Start: 803
• Page End: 807
• Publication Date: 2013-12-06
• Subjects: Heterocyclic compounds -- Periodicals; 547.59
• DOI: 10.1002/jhet.1905
• Languages: English
• ISSNs: 0022-152X

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <p>In the study of the synthesis of 2‐(2′‐hydroxy‐5′‐carboxyphenyl)‐2<italic>H</italic>‐benzotriazole, we found that decarboxy intermediate‐4‐((2‐nitrophenyl)diazenyl)phenol was obtained when using <italic>p</italic>‐hydroxybenzoic acid as coupling component. A convenient protocol for the synthesis of 2‐(2′‐hydroxy‐5′‐carboxyphenyl)‐2<italic>H</italic>‐benzotriazole is reported with methyl‐<italic>p</italic>‐hydroxybenzoate as coupling component. Different dizao components and different coupling components were also used for further investigation of <named-content content-type="reactionType" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink">decarboxylation</named-content>.</p> </abstract>