The impact of metabolic syndrome on serum total testosterone level in patients with erectile dysfunction. (June 2014)

• Record Type: Journal Article
• Authors: Aslan, Yilmaz; Guzel, Ozer; Balci, Melih; Tuncel, Altug; Yildiz, Muslum; Atan, Ali
• Is Part Of: Aging male. Volume 17:Number 2(2014:Jun.)
• Page Start: 76
• Page End: 80
• Publication Date: 2014-06
• Subjects: Aging -- Periodicals; Men -- Periodicals; Gerontology -- Periodicals; Men -- Health and hygiene -- Periodicals; Aging -- periodicals; Geriatric -- periodicals; Men -- periodicals; Aged -- periodicals; Aged, 80 and over -- periodicals; 612.67
• DOI: 10.3109/13685538.2014.895318
• Languages: English
• ISSNs: 1368-5538

Abstract

<abstract> <title>Abstract</title> <p> <italic>Objectives</italic>: To determine the association between metabolic syndrome (MetS) and serum testosterone levels (TT) in patients with erectile dysfunction (ED).</p> <p> <italic>Methods</italic>: This study included 280 ED patients above 40-years-of-age. Participants were divided into two groups according to 2005 criteria of International Diabetes Federation. The severity of ED was determined according to the International Index of Erectile Function-EF (IIEF-EF score; 0–10 severe ED, 11–25 mild to moderate ED). The severity of ED, serum TT levels and other MetS components were compared between the groups.</p> <p> <italic>Results</italic>: The mean age of the patients was 55.7 ± 8.2 years. One hundred eighteen patients (%42.1) had MetS. Sixty-eight patients with MetS (57.6%) and 71 patients without MetS (43.8%) had severe ED (<italic>p</italic> = 0.031). A total of 46 (16.4%) patients had hypogonadism. Hypogonadism was seen more prevalent in patients with MetS (22.9% vs. 11.7%, <italic>p</italic> = 0.013). Logistic regression analyses for ED risk factors demonstrated that abnormal FBG increased the relative risk of severe ED up to 10.7-fold (<italic>p</italic> < 0.001) but not presence of hypogonadism (<italic>p</italic> = 0.706).</p> <p> <italic>Conclusion</italic>: Metabolic syndrome was seen in almost half of the patients with ED. ED was more severe among MetS patients. Hypogonadism alone is a not risk factor for severe ED.</p> </abstract>