Visible‐Light‐Induced Formal [3+2] Cycloaddition for Pyrrole Synthesis under Metal‐Free Conditions1. Issue 22 (11th April 2014)

• Record Type: Journal Article
• Authors: Xuan, Jun; Xia, Xu‐Dong; Zeng, Ting‐Ting; Feng, Zhu‐Jia; Chen, Jia‐Rong; Lu, Liang‐Qiu; Xiao, Wen‐Jing
• Is Part Of: Angewandte Chemie international edition. Volume 53:Issue 22(2014)
• Page Start: 5653
• Page End: 5656
• Publication Date: 2014-04-11
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201400602
• Languages: English
• ISSNs: 1433-7851

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>A photocatalytic formal [3+2] cycloaddition of 2<italic>H</italic>‐azirines with alkynes has been achieved under irradiation by visible light in the presence of organic dye photocatalysts. This transformation provides efficient access to highly functionalized pyrroles in good yields and has been applied to the synthesis of drug analogues. A primary trial of photocascade catalysis merging energy transfer and redox neutral reactions was shown to be successful.</p> </abstract>