Citric Acid and the RNA World1. Issue 21 (19th May 2014)

• Record Type: Journal Article
• Authors: Müller, Ulrich F.; Tor, Yitzhak
• Is Part Of: Angewandte Chemie international edition. Volume 53:Issue 21(2014)
• Page Start: 5245
• Page End: 5247
• Publication Date: 2014-05-19
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201400847
• Languages: English
• ISSNs: 1433-7851

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>RNA world</bold>: The chelation of magnesium ions by citric acid prevents the magnesium‐induced aggregation of lipid vesicles and RNA degradation while promoting nonenzymatic RNA oligomerization. These findings suggest a unique role for this simple organic acid in supporting key processes in RNA world organisms.<boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgh27b5f1t" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>